Eletriptan hydrobromide

Cat. No.: OB0225WX-1950

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR.

Size:

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Product Overview

Description: Eletriptan hydrobromide is an orally bioavailable agonist that possesses specific binding affinity for the 5-HT1B/1D serotonin receptor subtypes.

Synonym: Eletriptan HBr; UK-116044; 177834-92-3; Relpax; Eletriptan monohydrobromide; Eletriptan (hydrobromide); (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole monohydrobromide; (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole hydrobromide; 5-[2-(benzenesulfonyl)ethyl]-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole;hydrobromide; 1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-, hydrobromide (1:1); 3-(((R)-1-Methyl-2-pyrrolidinyl)methyl)-5-(2-(phenylsulfonyl)ethyl)indole, monohydrobromide; 5-[2-(phenylsulfonyl)ethyl]-3-[(2R)-pyrrolidin-2-ylmethyl]-1H-indole hydrobromide; 1H-Indole, 3-(((2R)-1-methyl-2-pyrrolidinyl))methyl)-5-(2-(phenylsulfonyl)ethyl)-, monohydrobromide; 5-(2-(phenylsulfonyl)ethyl)-3-((2R)-pyrrolidin-2-ylmethyl)-1H-indole hydrobromide; 3-[[(R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]indole, monohydrobromide; eletriptanhydrobromide; MFCD08141806

CAS No.: 177834-92-3

Compound CID: 656631

Formula: C₂₂H₂₇BrN₂O₂S

Formula Weight: 463.43

Specification

Targets&IC50: 5-HT1B: 0.92 nM(Ki); 5-HT1D: 3.14 nM(Ki)

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Eletriptan hydrobromide is used in vascular pharmacology as a selective 5-HT1B/1D receptor agonist to study the constriction of intracranial blood vessels and the inhibition of neurogenic inflammation.