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DLin-MC3-DMA-d6
Cat. No.:
OB0626WX-3610
Appearance:
Liquid
Purity:
≥99% (deuterated forms, d1-d6)
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
DLin-MC3-DMA-d6 is a hexadeuterated stable isotope internal standard designed for high-precision quantification via gas or liquid chromatography-mass spectrometry. Its native unlabelled counterpart is an ionizable cationic lipid characterized. This structural framework allows for efficient, charge-mediated encapsulation of diverse nucleic acid payloads, supporting cellular uptake and downstream expression. Following systemic distribution, formulations utilizing this lipid exhibit tissue-specific accumulation across visceral organs and lymphoid compartments without elevating typical biomarkers of cellular toxicity.
Labeling:
Stable isotope-labeled
Synonyms:
4-(dimethyl-d3-amino)-butanoic acid, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester; Dilinoleyl-methyl-4-dimethylaminobutyrate-d6; MC3-d6
Formula:
C43H73D6NO2
Formula Weight:
648.1
Specification
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
DLin-MC3-DMA-d6 serves as a stable isotope-labeled analytical standard for quantitative analysis of the ionizable lipid DLin-MC3-DMA. It supports isotope dilution LC-MS/MS workflows, lipid formulation analysis, analytical calibration, and accurate quantification of ionizable lipid components.