Products
Online Inquiry
Dasotraline hydrochloride
Cat. No.:
0225LY-0640
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Dasotraline hydrochloride is a triple reuptake inhibitor that targets the transporters for dopamine, norepinephrine, and serotonin with IC50 values of 4 nM, 6 nM, and 11 nM, respectively.
Synonym:
675126-08-6; (1R,4S)-N-Desmethyl sertraline hydrochloride; Dasotraline HCl; Rac-trans-N-desmethyl sertraline hydrochloride; (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride; (1R,4S)-trans-Norsertraline hydrochloride; (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine; (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine HCl; (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine Hydrochlorid
CAS No.:
675126-08-6
Compound CID:
25192248
Formula:
C16H16Cl3N
Formula Weight:
328.66
Specification
Targets&IC50:
Dopamine: 4nM; Norepinephrine: 6nM; SERT: 11 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Dasotraline hydrochloride can be used in neuropsychiatric research to study the triple reuptake inhibition of dopamine, norepinephrine, and serotonin.
Library Information
Target:
5-HT receptor; Dopamine receptor; Serotonin transporter; Norepinephrine transporter
Receptor:
5-HT receptor; Dopamine receptor; Serotonin transporter; Norepinephrine transporter
Pathways:
GPCR/G protein signaling; Neuronal signaling
Plate Number:
AOCL-9
Plate Location:
c6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
83.3 mg/mL; 253.45 mM
