Products
Online Inquiry
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
Cat. No.:
OB0225WX-2053
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR.
Size:
Add to basket
Product Overview
Description:
Dapagliflozin ((2S)-1,2-propanediol, hydrate) is a selective, orally active small molecule that inhibits the sodium-glucose co-transporter type 2 (SGLT2), the primary protein responsible for renal glucose reabsorption.
Synonym:
BMS-512148 (2S)-1,2-propanediol, hydrate; Dapagliflozin propanediol monohydrate; 960404-48-2; Dapagliflozin propanediol; Farxiga; Dapagliflozin propylene glycolate hydrate; Dapagliflozin S-propylene glycol monohydrate; Dapagliflozin ((2S)-1,2-propanediol, hydrate); Dapagliflozin propylene glycol hydrate; (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol;(2S)-propane-1,2-diol;hydrate; (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, (2S)-propane-1,2-diol (1:1) monohydrate; Dapagliflozin propandiol monohydrate; (2S)-propane-1,2-diol--(1S)-1,5-anhydro-1-(4-chloro-3-(4-ethoxybenzyl)phenyl)-D-glucitol--water (1/1/1); (2S)-propane-1,2-diol--(1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol--water (1/1/1); MFCD28167768
CAS No.:
960404-48-2
Compound CID:
24906252
Formula:
C24H35ClO9
Formula Weight:
502.98
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Dapagliflozin ((2S)-1,2-propanediol, hydrate) is used in metabolic research as a potent SGLT2 inhibitor to investigate the mechanisms of renal glucose reabsorption and its impact on glycemic control.
Library Information
Target:
SGLT
Receptor:
SGLT2
Pathways:
GPCR/G protein signaling
Plate Number:
AOCL-27
Plate Location:
c6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 99.41 mM
ALogP:
1.682
HBA_Count:
2
HBD_Count:
6
Rotatable Bond:
7





