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Vitamin B12 test kit

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Cat. No.: OB0225WX-2053
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR.
Size:
Dapagliflozin ((2<i>S</i>)-1,2-propanediol, hydrate)
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Product Overview

Description: Dapagliflozin ((2S)-1,2-propanediol, hydrate) is a selective, orally active small molecule that inhibits the sodium-glucose co-transporter type 2 (SGLT2), the primary protein responsible for renal glucose reabsorption.
Synonym: BMS-512148 (2S)-1,2-propanediol, hydrate; Dapagliflozin propanediol monohydrate; 960404-48-2; Dapagliflozin propanediol; Farxiga; Dapagliflozin propylene glycolate hydrate; Dapagliflozin S-propylene glycol monohydrate; Dapagliflozin ((2S)-1,2-propanediol, hydrate); Dapagliflozin propylene glycol hydrate; (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol;(2S)-propane-1,2-diol;hydrate; (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, (2S)-propane-1,2-diol (1:1) monohydrate; Dapagliflozin propandiol monohydrate; (2S)-propane-1,2-diol--(1S)-1,5-anhydro-1-(4-chloro-3-(4-ethoxybenzyl)phenyl)-D-glucitol--water (1/1/1); (2S)-propane-1,2-diol--(1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol--water (1/1/1); MFCD28167768
CAS No.: 960404-48-2
Compound CID: 24906252
Formula: C24H35ClO9
Formula Weight: 502.98

Specification

Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Dapagliflozin ((2S)-1,2-propanediol, hydrate) is used in metabolic research as a potent SGLT2 inhibitor to investigate the mechanisms of renal glucose reabsorption and its impact on glycemic control.

Library Information

Target: SGLT
Receptor: SGLT2
Pathways: GPCR/G protein signaling
Plate Number: AOCL-27
Plate Location: c6
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 50 mg/mL; 99.41 mM
ALogP: 1.682
HBA_Count: 2
HBD_Count: 6
Rotatable Bond: 7
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