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CL4F8-6
Cat. No.:
OB0626WX-3850
Appearance:
Liquid
Purity:
≥98%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
CL4F8-6 is an ionizable cationic lipid featuring an apparent pKa of 6.14, engineered to construct stimuli-responsive lipid nanoparticles for systemic macromolecular delivery. This core framework achieves highly efficient transcript packaging to direct expression within hepatic tissue zones, while also facilitating the co-encapsulation of complex CRISPR-Cas9 nuclease assemblies to execute site-specific genomic knockdown and reduce serum carrier protein levels.
Synonyms:
7-(4-(dipropylamino)butyl)-7-hydroxytridecane-1,13-diyl bis(2-hexyloctanoate); 2766493-12-1; [7-[4-(dipropylamino)butyl]-13-(2-hexyloctanoyloxy)-7-hydroxytridecyl] 2-hexyloctanoate
CAS No.:
2766493-12-1
Compound CID:
170679977
Formula:
C51H101NO5
Formula Weight:
808.4
Specification
Solubility in Ethanol:
10 mg/mL
Storage:
Storage at -20°C.
Applications:
CL4F8-6 serves as a research lipid for developing and evaluating lipid nanoparticle formulations. It supports comparative formulation studies, optimization of lipid compositions, nucleic acid delivery research, and physicochemical characterization of lipid assemblies.