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Cholesterol-PEG2000-DBCO
Cat. No.:
OB0626WX-7
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Cholesterol-PEG2000-DBCO is a functionalized, PEGylated form of cholesterol tailored for bioorthogonal click chemistry applications, serving as a highly reactive anchor lipid for in vitro membrane engineering that incorporates into cell lipid bilayers with significantly greater efficiency and less internalization compared to DSPE-PEG2000-DBCO.
Conjugation:
DBCO-functionalized
Synonyms:
Cholesterol-PEG(2000)-dibenzocyclooctyne
Formula:
(C2H4O)nC49H65N3O4
Specification
Solubility in DMSO:
≥10 mg/mL
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
Cholesterol-PEG2000-DBCO serves as a functionalized PEG lipid reagent for incorporating bioorthogonal click chemistry functionality into lipid-based assemblies. It supports surface modification strategies for liposomes, lipid nanoparticles, and related delivery platforms through copper-free conjugation approaches with azide-containing molecules.