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Cholesta-3,5-dien-7-one

Cat. No.: OB0626WX-684
Appearance: Crystalline solid
Purity: ≥95%
Identity: Confirmed by NMR, TLC, and IR.
Size:
Cholesta-3,5-dien-7-one
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Product Overview

Description: Cholesta-3,5-dien-7-one is an endogenous oxysterol that functions as a highly selective negative allosteric modulator of GABAA receptor complexes.
Synonyms: Δ3,5-Cholestadien-7-one; CSD; 3,5-Cholestadien-7-one; .DELTA.3,5-Cholestadien-7-one; Cholesterol Impurity 56; Cholesterol Impurity 61; 7-keto-3,5-cholestadiene; Cholesta-3,5-diene-7-one; delta3,5-Cholestadien-7-one; (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-one; (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-7H-cyclopenta[a]phenanthren-7-one; (8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-one; (9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-7H-cyclopenta[a]phenanthren-7-one; 567-72-6
CAS No.: 567-72-6
Compound CID: 5283627
Formula: C27H42O
Formula Weight: 382.6

Specification

λmax: 278 nm
Solubility in Other Solvents: Chloroform: 10 mg/mL
Storage: Storage at -20°C.
Applications: Cholesta-3,5-dien-7-one serves as an oxo-functionalized cholesterol oxidation derivative standard for validating lipid peroxidation monitoring metrics, checking non-enzymatic degradation profiles, and analyzing the structural impact of sterol oxidation on lateral membrane packing.
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