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C6 1-Deoxyceramide (m18:1(14Z)/6:0)
Cat. No.:
OB0626WX-1731
Appearance:
Crystalline solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and IR.
Size:
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Product Overview
Description:
C6 1-Deoxyceramide (m18:1(14Z)/6:0) is a short-chain atypical sphingolipid featuring a 1-deoxysphingosine backbone characterized by an atypical cis double bond configuration. This unique class of deoxysphingolipids is synthesized endogenously when serine palmitoyltransferase undergoes a metabolic substrate shift, condensing palmitoyl-CoA with alanine instead of serine.
Synonyms:
N-((2S,3R,Z)-3-hydroxyoctadec-14-en-2-yl)hexanamide; Ceramide (m18:1/6:0); C6 Ceramide (m18:1/6:0); Cer(m18:1/6:0); N-hexanoyl-1-deoxy-4,5-dihydro-14Z-Sphingosine
Formula:
C24H47NO2
Formula Weight:
381.6
Specification
Solubility in DMSO:
>20 mg/mL
Solubility in Ethanol:
>30 mg/mL
Solubility in DMF:
>20 mg/mL
Solubility in Other Solvents:
Ethanol:PBS mixture: 0.5 mg/mL; PBS: <50 µg/mL
Storage:
Storage at -20°C.
Applications:
C6 1-Deoxyceramide (m18:1(14Z)/6:0) acts as a positionally distinct cis-double-bond-containing, short-chain non-canonical sphingolipid standard lacking the C1-hydroxyl group, serving to calibrate quantitative sphingolipidomic separation arrays and investigate atypical sphingoid base pathway kinetics during stress simulation assays.
