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C22 1-Deoxyceramide (m18:1(14Z)/22:0)
Cat. No.:
OB0626WX-1262
Appearance:
Crystalline solid
Purity:
≥95%
Identity:
Confirmed by TLC.
Size:
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Product Overview
Description:
C22 1-Deoxyceramide (m18:1(14Z)/22:0) is a long-chain atypical ceramide variant structured around a modified 1-deoxysphingosine core that possesses a 14-cis double bond instead of the classical 4-trans double bond configuration. These aberrant 1-deoxysphingolipids are generated when serine palmitoyltransferase drives the condensation of palmitoyl-CoA with alanine in place of the standard serine substrate. The compound serves as a premium reference material for studying biosynthetic exceptions and complex sphingolipid phenotypes.
Synonyms:
N-((2S,3R,Z)-3-hydroxyoctadec-14-en-2-yl)docosanamide; C22 Ceramide (m18:1/22:0); Cer(m18:1/22:0); N-docosanoyl-1-deoxy-4,5-dihydro-14Z-Sphingosine
Formula:
C40H79NO2
Formula Weight:
606.1
Specification
Solubility in DMSO:
>20 mg/mL
Solubility in Ethanol:
>30 mg/mL
Solubility in DMF:
>20 mg/mL
Solubility in Other Solvents:
Ethanol:PBS mixture: 0.5 mg/mL; PBS: <50 µg/mL
Storage:
Storage at -20°C.
Applications:
C22 1-Deoxyceramide (m18:1(14Z)/22:0) provides a structurally defined atypical sphingolipid matrix control for precise quantification in steroidomic workflows and serves as a tool for studying structural membrane aberrations, lipid raft disruptions, and downstream cytotoxicity cascades triggered by non-canonical sphingolipids.
