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C12 NBD-dihydro Cer (d18:0/12:0)
Cat. No.:
OB0626WX-3007
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by TLC and HPLC.
Size:
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Product Overview
Description:
C12 NBD-dihydro Cer (d18:0/12:0) is a fluorescently labeled ceramide analogue featuring a saturated bond at the C-4/C-5 locus of its sphingosine backbone. Developed as a specialized probe to map sphingolipid processing, this compound exhibits a modified substrate efficiency profile when interacting with neutral and alkaline ceramidases compared to its unsaturated counterparts, providing a valuable control for evaluating bond-saturation preferences in ceramidase assays.
Labeling:
NBD-labeled
Synonyms:
N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-dodecanamide; NBD Cer(d18:0/12:0); NBD Ceramide (d18:0/12:0); C12 NBD dihydro Ceramide (d18:0/12:0); C-12 NBD-dihydro-Ceramide; C12-NBD Sphinganine; N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine; N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl)-12-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]dodecanamide; 474943-05-0
CAS No.:
474943-05-0
Compound CID:
71311688
Formula:
C36H63N5O6
Formula Weight:
661.9
Specification
λmax:
229 nm nm; 333 nm nm; 465 nm
Solubility in DMSO:
20 mg/mL
Solubility in Ethanol:
20 mg/mL
Solubility in DMF:
30 mg/mL
Storage:
Storage at -20°C.
Applications:
C12 NBD-dihydro Cer (d18:0/12:0) provides a fluorescent lipid probe for investigating sphingolipid behavior and membrane-associated lipid processes. It supports chemical biology studies, lipid localization analysis, and characterization of sphingolipid distribution in experimental systems.
