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C12 Cer (d18:1/12:0)
Cat. No.:
OB0626WX-2127
Appearance:
Crystalline solid
Purity:
≥98%
Identity:
Confirmed by TLC and HPLC.
Size:
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Product Overview
Description:
C12 Cer is a naturally occurring sphingolipid metabolite generated through the hydrolysis of C12 sphingomyelin by acid sphingomyelinase. Serving as a primary metabolic substrate for acid ceramidase pathways, this medium-chain ceramide is a key analyte in sphingolipid storage disorders such as Farber disease, and its expression profile alters significantly within vascular tissues during gestational hypertensive complications.
Synonyms:
N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-dodecanamide; Cer(d18:1/12:0); C12 Ceramide; Ceramide (d18:1/12:0); N-Lauroyl-D-erythro-Sphingosine; N-lauroylsphingosine; dodecyl sphingosine; laurylsphingosine; 74713-60-3
CAS No.:
74713-60-3
Compound CID:
5283562
Formula:
C30H59NO3
Formula Weight:
481.8
Specification
Solubility in DMF:
0.5 mg/mL
Storage:
Storage at -20°C.
Applications:
C12 Cer (d18:1/12:0) acts as an analytically pure short-chain ceramide reference standard to calibrate quantitative sphingolipidomic separation arrays, trace metabolic intermediates, and investigate the biophysical effects of hydrophobic mismatch in model lipid bilayers.
