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Bithionol
Cat. No.:
0225LY-0692
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Bithionol was previously utilized as an active component in topical medications before being identified as a strong photosensitizer linked to severe skin conditions; consequently, its new drug application (NDA) approvals were rescinded on October 24, 1967.
Synonym:
Actamer; 97-18-7; 2,2'-Thiobis(4,6-dichlorophenol); Lorothidol; Actamer; Bithionol sulfide; Bithionolate; Bidiphen; Bisoxyphen; 2-Hydroxy-3,5-dichlorophenyl sulfide; Bis(2-hydroxy-3,5-dichlorophenyl) sulfide; Bis(3,5-dichloro-2-hydroxyphenyl) sulfide; 2,2'-sulfanediylbis(4,6-dichlorophenol); 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenyl sulfide; 6,6'-thiobis(2,4-dichlorophenol); 2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfanylphenol
CAS No.:
97-18-7
Compound CID:
2406
Formula:
C12H6Cl4O2S
Formula Weight:
356.05
Specification
Targets&IC50:
sAC: 4.0 μM
Relative Density:
1.61 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Bithionol can be used in microbiology and oncology to study its dual role as an anthelmintic and a potential anti-tumor agent.
Library Information
Target:
Adenylate cyclase; Parasite protein
Receptor:
sAC
Pathways:
GPCR/G protein signaling; Microbiology/Virology
Plate Number:
AOCL-9
Plate Location:
h9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
250 mg/mL; 702.15 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
21 mg/mL; 58.98 mM
ALogP:
6.122
HBA_Count:
0
HBD_Count:
2
Rotatable Bond:
2
