Products
Online Inquiry
Asialo Ganglioside GM1
Cat. No.:
OB0626WX-2565
Appearance:
Lyophilized powder
Purity:
≥98%
Identity:
Confirmed by TLC.
Size:
Add to basket
Product Overview
Description:
Asialo ganglioside GM1 is a prominent, non-sialylated glycosphingolipid constituent of cellular lipid rafts, typically generated via the enzymatic removal of sialic acid from ganglioside GM1 by neuraminidase. Characterized by a core primarily containing C18:0 fatty acyl chains, this glycolipid serves as a specialized surface receptor for bacterial flagellin, orchestrating host defense cascades such as calcium mobilization, ATP release, and ERK1/2 activation, while serving as a phenotypic marker for monitoring natural killer and CD8+ T cell population dynamics during viral respiratory responses.
Synonyms:
ASGM1; Asialo GM1; Gangliotetraosylceramide; Asialo GM1 ganglioside; Asialo GM1 glycolipid; Ganglio-N-tetraosylceramide; Ganglioside, asialo GM1; 71012-19-6
CAS No.:
71012-19-6
Compound CID:
6450363
Formula:
C62H114N2O23 (for stearoyl)
Specification
Storage:
Storage at -20°C.
Applications:
Asialo Ganglioside GM1 supports studies of glycosphingolipid structure, membrane organization, and carbohydrate-deficient ganglioside derivatives. It is utilized in lipid analysis workflows, structural characterization, and research investigating ganglioside-related molecular interactions.
