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Arnicolide D
Cat. No.:
0225LY-0556
Appearance:
Solid
Purity:
≥96%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Arnicolide D, a sesquiterpene lactone isolated from Centipeda minima, suppresses nasopharyngeal carcinoma (NPC) cell viability and HT-29 colon cancer cells by modulating the cell cycle, activating caspases, and inhibiting the STAT3 and PI3K/AKT/mTOR pathways.
Synonym:
34532-68-8; [(1S,3aR,5R,5aR,8aR,9S,9aR)-1,5,8a-trimethyl-2,8-dioxo-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,5-b]furan-9-yl] 2-methylprop-2-enoate; (3aR)-4,4a,7aalpha,8,9,9aalpha-Hexahydro-4alpha-(methacryloyloxy)-3beta,4abeta,8alpha-trimethylazuleno[6,5-b]furan-2,5(3H,3aalphaH)-dione; ArnicolideD; 11,13-Dihydrohelenalin methacrylate
CAS No.:
34532-68-8
Compound CID:
182199
Formula:
C19H24O5
Formula Weight:
332.39
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Arnicolide D can be used in cancer research to study the induction of apoptosis and the inhibition of STAT3 signaling in malignant cells.
Library Information
Target:
mTOR; PI3K; Caspase; STAT; Akt
Receptor:
Akt; Caspase; mTOR; PI3K; STAT3
Pathways:
PI3K/Akt/mTOR signaling; Apoptosis; JAK/STAT signaling; Cytoskeletal signaling; Proteases/Proteasome; Stem cell regulation
Plate Number:
AOCL-8
Plate Location:
b10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
4.16 mg/mL; 12.52 mM
