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Arachidonoyl-1-thio-glycerol
Cat. No.:
OB0626WX-3021
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by IR, TLC, and HPLC.
Size:
Add to basket
Product Overview
Description:
Arachidonoyl-1-thio-glycerol is a specialized thioester substrate analogue designed to match the structural architecture of the endocannabinoid 2-arachidonoylglycerol. Upon hydrolytic cleavage of its unstable thioester linkage by monoacylglycerol lipase, the molecule unmasks a reactive free thiol group that interacts colorimetrically with Ellman's reagent, providing a clear photometric readout for monitoring enzyme kinetics.
Synonyms:
5Z,8Z,11Z,14Z-eicosatetraenyl,1-thio glycerol; 1-S-Arachidonoyl-1-mercapto-2,3-propanediol; Arachidonoyl-1-thioglycerol; S-(2,3-dihydroxypropyl) (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate; (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenethioic Acid S-(2,3-Dihydroxypropyl) Ester; 5Z,8Z,11Z,14Z-Eicosatetraenoyl-1-thioglycerol; 5,8,11,14-Eicosatetraenethioic acid, S-[(2S)-2,3-dihydroxypropyl] ester, (5Z,8Z,11Z,14Z)-; 1309664-54-7
CAS No.:
1309664-54-7
Compound CID:
57496189
Formula:
C23H38O3S
Formula Weight:
394.6
Specification
λmax:
233 nm
Solubility in DMSO:
10 mg/mL
Solubility in Ethanol:
30 mg/mL
Solubility in DMF:
20 mg/mL
Solubility in Other Solvents:
Ethanol:PBS mixture: 0.25 mg/mL
Storage:
Storage at -80°C.
Applications:
Arachidonoyl-1-thio-glycerol provides a modified lipid substrate for biochemical studies involving arachidonic acid-derived glycerolipids. It supports lipid enzyme characterization, lipid transformation studies, and investigation of glycerolipid metabolism.
