Product Overview
Description:
AdipoUpX™ Human IGF1 MSCV Particle (Overexpression) is a professionally engineered vector particle providing efficient and stable overexpression of human IGF1. Insulin-like growth factor 1 is vital for growth, adipocyte differentiation, and glucose homeostasis. The MSCV system is optimized specifically for hematopoietic stem cells, stem cells, etc., making it a superior choice for investigating the endocrine and paracrine effects of IGF1 in stable cell lines. All viral systems undergo rigorous testing to ensure the highest quality and experimental repeatability.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
IGF1
Full Name:
Insulin like growth factor 1
Gene Symbol:
IGF; MGF; IGFI; IGF-I
Summary:
IGF1 encodes a protein structurally and functionally similar to insulin and is a member of a protein family involved in growth and development. The protein is synthesized as a precursor, processed into its mature form, secreted, and binds to a specific receptor to mediate its effects. Mutations in this gene lead to insulin-like growth factor I deficiency. Alternative splicing produces multiple transcript variants encoding different isoforms, which may undergo similar processing to generate functional proteins.
