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Abrocitinib
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Cat. No.:
OB0125LY-078
Size:
1 mg; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg
CAS No.:
1622902-68-4
Compound CID:
78323835
Specification
Description:
Abrocitinib is a specific and orally-active JAK1 inhibitor that interferes with cytokine signaling by inhibiting JAK1 to modulate immune cell function.
Formula Weight:
323.41
Stability:
3 years in powder form.
Applications:
Abrocitinib can be used for drug development for immune-related diseases.
Storage:
Storage at -20°C.
Formula:
C14H21N5O2S
Appearance:
Solid
Purity:
99.9%
Identity:
Confirmed by NMR and HPLC.
Targets&IC50:
JAK2: 803 nM; JAK1: 29 nM; TYK2: 1253 nM
Relative Density:
1.36 g/cm3
Library Information
Plate Number:
AOCL-18
Plate Location:
e11
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem cells
Targets:
JAK
Receptors:
JAK; JAK1; JAK2
DMSO Max Solubility (mg/mL):
120 mg/mL
DMSO Max Solubility (mM):
371.05 mM
ALogP:
1.101
HBA_Count:
4
HBD_Count:
2
Rotatable Bond:
6