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AA-T3A-C12
Cat. No.:
OB0626WX-3849
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
AA-T3A-C12 is a target-directed ionizable cationic lipidoid comprising a core polyamine scaffold linked to an anisamide sigma-receptor ligand and four hydrophobic 12-carbon tails. This multi-functional architecture co-assembles into lipid nanoparticles that home specifically to sigma-receptor-expressing cells, delivering silencing RNA to downregulate fibrotic molecular chaperones and alleviate chemically induced hepatic fibrosis.
Synonyms:
N-(3-(bis(3-(bis(2-hydroxydodecyl)amino)propyl)amino)propyl)-4-methoxybenzamide; 2938207-23-7
CAS No.:
2938207-23-7
Compound CID:
168007147
Formula:
C65H126N4O6
Formula Weight:
1059.7
Specification
λmax:
254 nm
Solubility in Ethanol:
10 mg/mL
Storage:
Storage at -20°C.
Applications:
AA-T3A-C12 serves as a synthetic lipid for investigating ionizable lipid design and lipid nanoparticle development. It supports formulation optimization, nucleic acid encapsulation research, structure–activity relationship studies, and characterization of lipid-mediated delivery systems.