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(±)8(9)-EET
Cat. No.:
OB0626WX-3337
Appearance:
Liquid
Purity:
≥98%
Identity:
Confirmed by IR, TLC, and HPLC.
Size:
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Product Overview
Description:
(±)8(9)-EET is a racemic epoxyeicosatrienoic acid regioisomer synthesized from arachidonic acid via cytochrome P450 monooxygenase pathways, serving as a major lipid mediator within cortical renal architectures. This versatile epoxide modulates gene transcription by interacting with peroxisome proliferator-activated receptor alpha, dampens cytokine-induced pro-inflammatory signaling, acts as a functional substrate for cyclooxygenase tracks, and drives stereospecific, arachidonate-dependent pre-glomerular vasoconstriction.
Synonyms:
rel-(8S,9R)-epoxy-5Z,11Z,14Z-eicosatrienoic acid; (±)8,9-EpETrE
Formula:
C20H32O3
Formula Weight:
320.5
Specification
Solubility in DMSO:
50 mg/mL
Solubility in Ethanol:
50 mg/mL
Solubility in DMF:
50 mg/mL
Solubility in Other Solvents:
PBS: 1 mg/mL
Storage:
Storage at -20°C.
Applications:
(±)8(9)-EET serves as a reference compound for studying epoxyeicosatrienoic acid species and oxidized arachidonic acid metabolism. It supports lipidomic profiling, analytical identification of epoxy fatty acid derivatives, and investigation of eicosanoid transformation pathways.
