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4A3-SC10
Cat. No.:
OB0626WX-3642
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
4A3-SC10 is an ionizable cationic lipid featuring an apparent pKa of 6.57, optimized for the structural assembly of responsive lipid nanoparticles. This chemical architecture facilitates precise, charge-mediated nucleic acid encapsulation, directing the systemic localization of encapsulated transcripts toward visceral metabolic organs and lymphoid tissue networks while driving robust intracellular reporter expression across various epithelial and carcinoma lines.
Synonyms:
4A3-SC-10; 1857340-80-7
CAS No.:
1857340-80-7
Compound CID:
178273441
Formula:
C83H155N3O16S4
Formula Weight:
1579.4
Specification
Solubility in Other Solvents:
Methyl acetate: ≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
4A3-SC10 serves as an ionizable lipid component for lipid nanoparticle formulation research. It supports the development of delivery systems, investigation of lipid structure-function relationships, and characterization of nanoparticle properties.