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2-O-ethyl PAF C-16
Cat. No.:
OB0626WX-3309
Appearance:
Lyophilized powder
Purity:
≥98%
Identity:
Confirmed by TLC.
Size:
Add to basket
Product Overview
Description:
2-O-ethyl PAF C-16 is a synthetic phospholipid congener of platelet-activating factor featuring a stable ethyl ether modification at the sn-2 position of the glycerol backbone. This amphiphilic lipid serves as a tailored tool for probing platelet activation dynamics, exhibiting shifted agonist potency profiles compared to carbamate-modified analogues while driving cation-dependent granulocyte aggregation cascades and mediating pathway desensitization under chelated environments.
Synonyms:
1-O-hexadecyl-2-O-ethyl-sn-glyceryl-3-phosphorylcholine; [(2R)-2-ethoxy-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate; (2R)-2-Ethoxy-3-(hexadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate; (R)-2-Ethoxy-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate; 78858-42-1
CAS No.:
78858-42-1
Compound CID:
24779410
Formula:
C26H56NO6P
Formula Weight:
509.7
Specification
Solubility in DMSO:
<20 µg/mL
Solubility in Ethanol:
>10 mg/mL
Solubility in DMF:
>125 µg/mL
Solubility in Other Solvents:
PBS: >11 mg/mL
Storage:
Storage at -20°C.
Applications:
2-O-ethyl PAF C-16 serves as a PAF analog for biochemical studies of ether phospholipid derivatives. It supports investigation of PAF-related lipid signaling, structural characterization, and comparative analysis of modified phospholipid compounds.
