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(±)16(17)-DiHDPA
Cat. No.:
OB0626WX-2251
Appearance:
Liquid
Purity:
≥98%
Identity:
Confirmed by IR, TLC, and HPLC.
Size:
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Product Overview
Description:
(±)16(17)-DiHDPA is an oxygenated vicinal diol fatty acid produced through the selective action of cytochrome P450 epoxygenases on the omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA). This bioactive docosanoid metabolite functions as a potent regulator of vascular remodeling and tumor progression, demonstrating a strong capacity to inhibit VEGF-induced angiogenesis and suppress cancer cell metastasis in vivo.
Synonyms:
(±)16,17-dihydroxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid; 16,17-DiHDPE; (+-)-16,17-dihydroxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid; (+/-)-16,17-dihydroxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid; 16,17-dihydroxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid; 1345275-27-5
CAS No.:
1345275-27-5
Compound CID:
16061147
Formula:
C22H34O4
Formula Weight:
362.5
Specification
Solubility in DMSO:
50 mg/mL
Solubility in Ethanol:
50 mg/mL
Solubility in DMF:
50 mg/mL
Solubility in Other Solvents:
PBS: 0.25 mg/mL
Storage:
Storage at -20°C.
Applications:
(±)16(17)-DiHDPA serves as a reference compound for studies of oxygenated docosapentaenoic acid metabolites and specialized lipid mediators. It supports targeted lipidomic analysis, structural characterization, and investigations of polyunsaturated fatty acid oxidation, lipid mediator biosynthesis, and metabolic pathway analysis.
