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(±)14(15)-EET-SI
Cat. No.:
OB0626WX-2936
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by TLC and HPLC.
Size:
Add to basket
Product Overview
Description:
(±)14(15)-EET-SI is a metabolically stabilized methyl sulfonamide analogue of 14(15)-epoxyeicosatrienoic acid engineered to resist cellular degradation pathways such as beta-oxidation and membrane esterification. The compound functions as a functional mimetic of native epoxides, operating at the cellular level to drive vascular smooth muscle relaxation, induce kinase phosphorylation, and stimulate mitogenic cascades in epithelial systems.
Synonyms:
N-(methylsulfonyl)-13-(3-pentyloxiranyl)-5Z,8Z,11Z-tridecatrienamide; 14,15-EpETrE-SI; 14(15)-EET-SI; 14(15)-EET-sulfonimide; 218461-97-3; (5Z,8Z,11Z)-N-methylsulfonyl-13-(3-pentyloxiran-2-yl)trideca-5,8,11-trienamide; 14,15-EET-SI; (5Z,8Z,11Z)-N-(Methylsulfonyl)-13-(3-pentyloxiran-2-yl)trideca-5,8,11-trienamide
CAS No.:
218461-97-3
Compound CID:
91886141
Formula:
C21H35NO4S
Formula Weight:
397.6
Specification
Solubility in DMSO:
10 mg/mL
Solubility in Ethanol:
10 mg/mL
Solubility in DMF:
10 mg/mL
Solubility in Other Solvents:
Ethanol:PBS mixture: 0.3 mg/mL
Storage:
Storage at -20°C.
Applications:
(±)14(15)-EET-SI serves as a stable isotope-labeled reference compound for quantitative analysis of epoxyeicosatrienoic acid metabolites. It supports isotope dilution workflows, LC-MS/MS-based lipid mediator profiling, analytical calibration, and structural identification of epoxy fatty acid derivatives.