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13,14-dihydro-15-keto PGE2-d4
Cat. No.:
OB0626WX-2892
Appearance:
Liquid
Purity:
≥99% (deuterated forms, d1–d4)
Identity:
Confirmed by TLC and HPLC.
Size:
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Product Overview
Description:
13,14-dihydro-15-keto PGE2-d4 is a deuterated internal standard optimized for mass spectrometric quantification. The native analyte is the primary inactivated metabolite of prostaglandin E2 circulating in plasma, generated via sequential reduction by 15-oxo-prostaglandin Δ13 reductase, and exhibits distinct structural variations that correlate with specific tissue metabolic flux and gestational profiles.
Labeling:
Stable isotope-labeled
Synonyms:
9,15-dioxo-11α-hydroxy-prost-5Z-en-1-oic-3,3,4,4-d4 acid; 13,14-dihydro-oxo-PGE2-d4; PGEM-d4; 13,14-dihydro-15-keto Prostaglandin E2-d4
Formula:
C20H28D4O5
Formula Weight:
356.5
Specification
Solubility in DMSO:
50 mg/mL
Solubility in Ethanol:
50 mg/mL
Solubility in DMF:
50 mg/mL
Solubility in Other Solvents:
PBS: 1 mg/mL
Storage:
Storage at -20°C.
Applications:
13,14-dihydro-15-keto PGE2-d4 serves as a stable isotope-labeled reference standard for quantitative lipid mediator analysis, LC-MS/MS method development, and isotope dilution-based measurement of prostaglandin metabolites. It supports accurate identification, calibration, and profiling of prostaglandin E2 metabolic products in lipidomics workflows.
