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12(S)-HETE-d8
Cat. No.:
OB0626WX-3178
Appearance:
Liquid
Purity:
≥99% (deuterated forms, d1-d8)
Identity:
Confirmed by TLC and HPLC.
Size:
Add to basket
Product Overview
Description:
12(S)-HETE-d8 is an octadeuterated stable isotope internal standard engineered for precision calibration in mass spectrometry assays. The target native lipid is a chiral monohydroxy fatty acid generated via stereospecific 12(S)-lipoxygenase-mediated oxidation of arachidonic acid, existing alongside non-enzymatic radical autoxidation variants and cytochrome P450-derived 12(R) stereoisomers to serve as a key benchmark for mapping distinct lipid oxidation tracks.
Labeling:
Stable isotope-labeled
Synonyms:
12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid; 12(S)-Hydroxyeicosatetraenoic Acid-d8; 2(S)-HETE D8; (5Z,8Z,10E,12S,14Z)-5,6,8,9,11,12,14,15-octadeuterio-12-hydroxyicosa-5,8,10,14-tetraenoic acid; 12S-HETE-d8; 84807-90-9; 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid-d8; (5Z,8Z,10E,12S,14Z)-12-Hydroxy(5,6,8,9,11,12,14,15-~2~H_8_)icosa-5,8,10,14-tetraenoic acid; (5Z,8Z,10E,12S,14Z)-12-Hydroxy-5,8,10,14-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid
CAS No.:
84807-90-9
Compound CID:
6914100
Formula:
C20H24D8O3
Formula Weight:
328.5
Specification
λmax:
237 nm
Solubility in Other Solvents:
Na2CO3: 2 mg/mL; PBS: 0.8 mg/mL
Storage:
Storage at -20°C.
Applications:
12(S)-HETE-d8 provides a stable isotope-labeled analytical standard for quantitative analysis of hydroxyeicosatetraenoic acid metabolites. It supports isotope dilution LC-MS/MS workflows, analytical calibration, and accurate profiling of lipoxygenase-derived lipid products.
