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(±)12-HpETE
Cat. No.:
OB0626WX-3385
Appearance:
Liquid
Purity:
≥96%
Identity:
Confirmed by TLC and HPLC.
Size:
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Product Overview
Description:
(±)12-HpETE is a racemic monohydroperoxy polyunsaturated fatty acid mixture comprising equal proportions of the 12(R) and 12(S) enantiomers, generated through the non-enzymatic, radical-driven peroxidation of arachidonic acid matrices. This highly reactive hydroperoxide intermediate can undergo chemical reduction to yield the corresponding, more stable hydroxylated derivative (±)12-HETE, serving as a critical structural probe for mapping non-enzymatic oxidative lipid cascades.
Synonyms:
12-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid; 12-Hpete, (RS)-; 71030-35-8; (+/-)12-HpETE; 12-Hydroperoxyarachidonic acid, (RS)-; (5Z,8Z,10E,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid; 5,8,10,14-Eicosatetraenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,14Z)-; (+/-)-12-hydroperoxyarachidonic acid; 12-hydroperoxy-(z,z,e,z)-5,8,10,14-eicosatetraenoic acid
CAS No.:
71030-35-8
Compound CID:
5283175
Formula:
C20H32O4
Formula Weight:
336.5
Specification
λmax:
237 nm
Solubility in Other Solvents:
Na2CO3: 2 mg/mL; PBS: 0.5 mg/mL
Storage:
Storage at -80°C.
Applications:
(±)12-HpETE is used as a reference compound for studying hydroperoxy arachidonic acid metabolites and oxidative lipid pathways. It supports lipidomic profiling, structural characterization, and investigation of oxygenated fatty acid formation.
