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11-trans Leukotriene D4
Cat. No.:
OB0626WX-3268
Appearance:
Liquid
Purity:
≥97%
Identity:
Confirmed by HPLC.
Size:
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Product Overview
Description:
11-trans Leukotriene D4 is a geometrically rearranged structural isomer of leukotriene D4 that arises via spontaneous, temperature-dependent isomerization across the C-11 double bond during extended storage. This trans-eicosanoid variant retains an attenuated capacity to engage leukotriene receptors, exhibiting a fractional level of the smooth muscle contractile potency characteristic of the native cis configuration.
Synonyms:
5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid; 11-trans LTD4; 11-trans-LTD4; 11-trans-Leukotriene D4; (5S,6R,7E,9E,11E,14Z)-6-[(2R)-2-amino-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid; 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E14Z-eicosatetraenoic acid; 11-TRANSLEUKOTRIENED4; 79768-40-4
CAS No.:
79768-40-4
Compound CID:
5283135
Formula:
C25H40N2O6S
Formula Weight:
496.7
Specification
λmax:
278 nm
Solubility in DMSO:
50 mg/mL
Solubility in Ethanol:
50 mg/mL
Solubility in DMF:
50 mg/mL
Solubility in Other Solvents:
PBS: 0.1 mg/mL
Storage:
Storage at -20°C.
Applications:
11-trans Leukotriene D4 serves as a leukotriene isomer reference compound for analytical characterization of cysteinyl leukotriene derivatives. It supports lipid mediator profiling, LC-MS/MS analysis, and comparative studies of leukotriene structures.
