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11-Deoxy-11-methylene PGD2
Cat. No.:
OB0626WX-3446
Appearance:
Liquid
Purity:
≥98%
Identity:
Confirmed by TLC and HPLC.
Size:
Add to basket
Product Overview
Description:
11-Deoxy-11-methylene PGD2 is a novel, chemically stable isosteric analogue of prostaglandin D2 engineered by replacing the native, unstable 11-keto group with an exocyclic methylene modification. This unique structural architecture overcomes the chemical instability and short half-life characteristic of the parent eicosanoid, providing a resilient chemical scaffold for dissecting divergent prostanoid receptor signaling cascades across diverse cellular assays.
Synonyms:
9α,15S-dihydroxy-11-methylene-prosta-5Z,13E-dien-1-oic acid; 11-deoxy-11-methylene-PGD2; 11-deoxy-11-methylene Prostaglandin D2; (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-methylidenecyclopentyl]hept-5-enoic acid; 11-Deoxy-11-methyleneprostaglandin D2; 11-deoxy-11-methylene-Prostaglandin D2; 9S,15S-dihydroxy-11-methylene-5Z,13E-prostadienoic acid; Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-methylene-, (5Z,9alpha,13E,15S)-; 9.alpha.,15S-Dihydroxy-11-methyleneprosta-5Z,13E-dien-1-oic acid; (5Z,9alpha,13e,15s)-9,15-dihydroxy-11-methylene-prosta-5,13-dien-1-oicacid
CAS No.:
100648-29-1
Compound CID:
5283095
Formula:
C21H34O4
Formula Weight:
350.5
Specification
Solubility in DMSO:
100 mg/mL
Solubility in Ethanol:
100 mg/mL
Solubility in DMF:
100 mg/mL
Solubility in Other Solvents:
PBS: 3.75 mg/mL
Storage:
Storage at -20°C.
Applications:
11-Deoxy-11-methylene PGD2 is utilized as a prostaglandin analog reference compound for eicosanoid analysis. It supports structural characterization, lipid mediator profiling, and investigation of modified prostanoid derivatives.
