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1-Stearoyl-2-oleoyl-sn-glycero-3-PE
Cat. No.:
OB0626WX-3889
Appearance:
Crystalline solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, IR, and HPLC.
Size:
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Product Overview
Description:
1-Stearoyl-2-oleoyl-sn-glycero-3-PE is a zwitterionic phosphatidylethanolamine helper lipid incorporating a saturated stearic acid anchor and a monounsaturated oleyl chain. This amphiphilic structural component modulates lateral phase separation and curvature strain within lipid bilayers, making it an essential formulation tool for creating lipid nanoparticles optimized for the intracellular transport of messenger RNA and nuclear-targeted plasmid DNA vectors.
Synonyms:
9Z-octadecenoic acid, 1R-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxooctadecyl)oxy]ethyl ester; 1-Octadecanoyl-2-(9Z)-Octadecenoyl-sn-glycero-3-Phosphatidylethanolamine; 1-Octadecanoyl-2-(9Z)-Octadecenoyl-sn-glycero-3-Phosphoethanolamine; 18:0-18:1 PE; PE(18:0/18:1); 1-Stearoyl-2-Oleoyl-sn-glycero-3-Phosphoethanolamine; 1,2-SOPE; 6418-95-7
CAS No.:
6418-95-7
Compound CID:
470676720
Formula:
C41H80NO8P
Formula Weight:
746.1
Specification
Solubility in Ethanol:
30 mg/mL
Storage:
Storage at -20°C.
Applications:
1-Stearoyl-2-oleoyl-sn-glycero-3-PE serves as a phosphatidylethanolamine reference lipid for investigating membrane architecture and lipid dynamics. It supports liposome formulation, membrane fusion studies, lipidomic profiling, structural characterization, and lipid–protein interaction research.