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Indomethacin
Cat. No.:
OB0225LY-0447
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties by reducing prostaglandin synthesis through inhibition of cyclooxygenase (COX).
Synonym:
Indocin; Indometacine; Indomethacine; Indometacin; 53-86-1; 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid; 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-; 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid; N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid
CAS No.:
53-86-1
Compound CID:
3715
Formula:
C19H16ClNO4
Formula Weight:
357.79
Specification
Relative Density:
1.32 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Indomethacin can be used in inflammation biology studies to explore the role of prostaglandins in the inflammatory response.
Library Information
Targets:
Phospholipase; COX; PDE
Receptors:
COX-1; COX-2; PDE2; PLA2
Pathways:
Metabolism; Neuronal signaling; Immunology/Inflammation; Autophagy
Plate Number:
AOCL-6
Plate Location:
g4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
50 mg/mL; 139.75 mM
Ethanol Max Solubility:
17.9 mg/mL; 50 mM
Solubility:
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.58 mg/mL (10.01 mM)
