Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
DGAT1-IN-1
Cat. No.:
0225LY-0723
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
DGAT1-IN-1 is a high-potency inhibitor of diacylglycerol O-acyltransferase type 1 (DGAT1), featuring an IC50 value below 10 nM.
Synonym:
1449779-49-0; 2-(trans-4-(4-(2-((4-(Trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid; 2-[4-[4-[2-[[4-(trifluoromethoxy)phenyl]methylcarbamoyl]imidazo[1,2-a]pyridin-6-yl]phenyl]cyclohexyl]acetic acid; 2-((1r,4r)-4-(4-(2-((4-(trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid; (4-{4-[2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl)acetic acid; Rel-2-((1r,4r)-4-(4-(2-((4-(Trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
CAS No.:
1449779-49-0
Compound CID:
71696573
Formula:
C30H28F3N3O4
Formula Weight:
551.56
Specification
Targets&IC50:
DGAT-1: < 10 nM
Relative Density:
1.36 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
DGAT1-IN-1 can be used in preclinical metabolic studies to evaluate the role of DGAT1 in controlling intestinal fat absorption.
Library Information
Target:
DGAT1
Receptor:
DGAT1
Pathways:
Metabolism
Plate Number:
AOCL-10
Plate Location:
c10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
20 mg/mL; 36.26 mM





