Products
Online Inquiry
Bufotalin
Cat. No.:
OB0225WX-1989
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Bufotalin is a steroid lactone and a prominent toxic constituent found in the parotid gland secretions of toads.
Synonym:
Bufotaline; 471-95-4; Bufotaline; [(3S,5R,8R,9S,10S,13R,14S,16S,17R)-3,14-dihydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] acetate; Bufa-20,22-dienolide, 16-(acetyloxy)-3,14-dihydroxy-, (3beta,5beta,16beta)-; 3beta-14,16beta-Trihydroxy-5beta-bufa-20,22-dienolide; 3beta,14,16beta-Trihydroxy-5beta-bufa-20,22-dienolide 16-acetate; 5beta-Bufa-20,22-dienolide, 3beta,14,16beta-trihydroxy-, 16-acetate; Bufa-20,22-dienolide, 16-(acetyloxy)-3,14-dihydroxy-, (3.beta.,5.beta.,16.beta.)-; ((3S,5R,8R,9S,10S,13R,14S,16S,17R)-3,14-dihydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta(a)phenanthren-16-yl) acetate; 5.beta.-Bufa-20,22-dienolide, 3.beta.,14,16.beta.-trihydroxy-, 16-acetate; (3S,5R,8R,9S,10S,13R,14S,16S,17R)-3,14-dihydroxy-10,13-dimethyl-17-(2-oxo-2H-pyran-5-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl acetate
CAS No.:
471-95-4
Compound CID:
12302120
Formula:
C26H36O6
Formula Weight:
444.56
Specification
Relative Density:
1.0942 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Bufotalin is utilized in oncology and cardiovascular research as a cardiotonic steroid to study its induction of apoptosis in cancer cells through the modulation of the mitochondrial pathway.
Library Information
Target:
Reactive oxygen species
Receptor:
Reactive oxygen species
Pathways:
Metabolism; Apoptosis; NF-κB; Immunology/Inflammation
Plate Number:
AOCL-26
Plate Location:
e2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 123.72 mM





