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CP-640186 hydrochloride
Cat. No.:
OB0225WX-1673
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
CP-640186 hydrochloride is an isozyme-nonselective inhibitor of acetyl-CoA carboxylase, showing potent activity against rat liver ACC1 (IC50: 53 nM) and skeletal muscle ACC2 (IC50: 61 nM).
Synonym:
CP 640186 HCl; 591778-70-0; CP-640186 (hydrochloride); (R)-anthracen-9-yl(3-(morpholine-4-carbonyl)-[1,4'-bipiperidin]-1'-yl)methanone hydrochloride; CP-640186 Hcl; 591778-70-0 (HCl); (3R)-1'-(anthracene-9-carbonyl)-3-(morpholine-4-carbonyl)-1,4'-bipiperidine hydrochloride; [(3R)-1-[1-(anthracene-9-carbonyl)piperidin-4-yl]piperidin-3-yl]-morpholin-4-ylmethanone;hydrochloride; CP 640186 hydrochloride; CP 640186 HCl
CAS No.:
591778-70-0
Compound CID:
23589188
Formula:
C30H36ClN3O3
Formula Weight:
522.08
Specification
Targets&IC50:
ACC1: 53 nM; ACC2: 61 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
CP-640186 hydrochloride is applied in metabolic research as a potent dual inhibitor of Acetyl-CoA Carboxylase (ACC1 and ACC2) to study the regulation of fatty acid oxidation and synthesis.
Library Information
Target:
ACC
Receptor:
ACC1; ACC2
Pathways:
Metabolism
Plate Number:
AOCL-22
Plate Location:
d8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 95.77 mM
