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Foscenvivint (ICG-001)
Cat. No.:
OB0225WX-2507
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Foscenvivint (ICG-001) is a small molecule antagonist of Wnt/beta-catenin-mediated transcription that specifically binds to the CREB-binding protein (CBP) with an IC50 of 3 micromolar.
Synonym:
780757-88-2 (relative stereochemistry)
CAS No.:
780757-88-2 (relative stereochemistry); 847591-62-2 (absolute stereochemistry)
Formula:
C33H32N4O4
Formula Weight:
548.63
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Foscenvivint (ICG-001) is used in developmental and oncology research to investigate the selective antagonism of the Wnt/beta-catenin signaling pathway by disrupting the interaction between beta-catenin and CBP.
Library Information
Target:
Epigenetic reader domain; Wnt/β-Catenin
Pathways:
Stem cells & Wnt
Plate Number:
L6700-04
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 182.27 mM
ALogP:
4.065
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
6
