Fexaramine

Cat. No.: OB0225WX-2653

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Fexaramine is a high-potency farnesoid X receptor (FXR) agonist (EC50: 25 nM) characterized by its lack of cross-reactivity with other nuclear receptors such as RXR, PPAR, or LXR.

Synonym: 574013-66-4; Methyl (E)-3-(3-(N-((4'-(dimethylamino)-[1,1'-biphenyl]-4-yl)methyl)cyclohexanecarboxamido)phenyl)acrylate; FEX; methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-[4-(dimethylamino)phenyl]phenyl]methyl]amino]phenyl]prop-2-enoate; 2-Propenoic acid, 3-(3-((cyclohexylcarbonyl)((4'-(dimethylamino)(1,1'-biphenyl)-4-yl)methyl)amino]phenyl)-, methyl ester; 3-[3-[(cyclohexylcarbonyl)-[[4'-(dimethylamino)-[1,1'-biphenyl]-4-yl]methyl]amino]phenyl]-2-propenoicacidmethylester; MFCD09971007; 2-Propenoic acid, 3-[3-[(cyclohexylcarbonyl)[[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]methyl]amino]phenyl]-, methyl ester; Methyl (Z)-3-[3-[cyclohexanecarbonyl-[[4-(4-dimethylaminophenyl)phenyl]methyl]amino]phenyl]prop-2-enoate

CAS No.: 574013-66-4

Compound CID: 5326713

Formula: C₃₂H₃₆N₂O₃

Formula Weight: 496.64

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Fexaramine is employed in metabolic research as a potent and selective FXR agonist to investigate the transcriptional regulation of bile acid, lipid, and glucose metabolism in hepatic and intestinal models.