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GW9662
Cat. No.:
0225LY-0916
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
GW9662 is a specific antagonist of PPARγ with an IC50 of 3.3 nM in cell-free environments, showing up to 1000-fold greater selectivity for PPARγ over the alpha and delta subtypes in cellular assays.
Synonym:
GW 9662; 22978-25-2; 2-Chloro-5-nitro-N-phenylbenzamide; 2-Chloro-5-nitrobenzanilide; GW-9662; 2-Chloro-5-nitro-N-4-phenylbenzamide; benzamide, 2-chloro-5-nitro-N-phenyl-; MFCD01215270; 2-Chloro-5-nitro-N-phenyl-benzamide; 2-Chloro-5-nitro- N -phenylbenzamide; Benzamide,2-chloro-5-nitro-N-phenyl-; Tocris-1508
CAS No.:
22978-25-2
Compound CID:
644213
Formula:
C13H9ClN2O3
Formula Weight:
276.68
Specification
Targets&IC50:
PPARγ: 3.3 nM
Relative Density:
1.44 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GW9662 can be used in cell signaling research to examine the selective and irreversible antagonism of the PPAR-gamma receptor.
Library Information
Target:
PPAR
Receptor:
PPARα; PPARγ; PPARδ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-12
Plate Location:
g7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
255 mg/mL; 921.64 mM
Ethanol Max Solubility:
6.9 mg/mL; 24.94 mM
ALogP:
3.173
HBA_Count:
1
HBD_Count:
1
Rotatable Bond:
3
