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CGS 15435
Cat. No.:
0225LY-0855
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
CGS 15435 is a high-potency thromboxane (TxA2) synthetase inhibitor (IC50: 1 nM) that displays significantly higher selectivity for its target compared to its effects on liposynthase, cyclooxygenase, and PGI2 synthase.
Synonym:
95853-92-2; 5-Chloro-1-methyl-2-(3-pyridyl)-3-indolehexanoic acid; 6-(5-chloro-1-methyl-2-pyridin-3-ylindol-3-yl)hexanoic acid; 3-(5-carboxypentyl)-5-chloro-1-methyl-2-(3-pyridyl)indole; 6-(5-Chloro-1-methyl-2-pyridin-3-yl-1H-indol-3-yl)-hexanoic acid
CAS No.:
95853-92-2
Compound CID:
129519
Formula:
C20H21ClN2O2
Formula Weight:
356.85
Specification
Targets&IC50:
TXA2: 1 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
CGS 15435 can be used in enzyme research to explore the inhibition of thromboxane synthase.
Library Information
Target:
TXAS
Receptor:
TXA2R
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-12
Plate Location:
a4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
3.57 mg/mL; 10 mM
