Seladelpar

Cat. No.: 0225LY-0888

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Seladelpar is a pharmaceutical agent that has been evaluated in clinical trials for the treatment of hyperlipidemia.

Synonym: MBX 8025; 851528-79-5; MBX-8025; (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid; 2-[4-[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl-2-methylphenoxy]acetic acid; ((4-(((2R)-2-Ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenyl)oxy)acetic acid; Acetic acid, (4-(((2R)-2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)-; Acetic acid, 2-(4-(((2R)-2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)-

CAS No.: 851528-79-5

Compound CID: 11236126

Formula: C₂₁H₂₃F₃O₅S

Formula Weight: 444.46

Specification

Targets&IC50: PPARδ: 2 nM (EC50); PPARα: 1600 nM (EC50)

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Seladelpar can be used in liver disease research to evaluate the selective agonism of PPAR delta in treating primary biliary cholangitis (PBC).