PF-06424439 methanesulfonate

Cat. No.: 0225LY-0720

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: PF-06424439 methanesulfonate is a selective and potent imidazopyridine inhibitor of DGAT2 (IC50: 14 nM) that is orally active, shows noncompetitive inhibition relative to acyl-CoA, and demonstrates slow reversibility.

Synonym: 1469284-79-4; PF-06424439 Mesylate; [(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinylmethanonemethanesulfonate; [(3R)-1-[2-[1-(4-chloropyrazol-1-yl)cyclopropyl]-1H-imidazo[4,5-b]pyridin-5-yl]piperidin-3-yl]-pyrrolidin-1-ylmethanone;methanesulfonic acid; (R)-(1-(2-(1-(4-chloro-1H-pyrazol-1-yl)cyclopropyl)-3H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone methanesulfonate

CAS No.: 1469284-79-4

Compound CID: 89854212

Formula: C₂₃H₃₀ClN₇O₄S

Formula Weight: 536.05

Specification

Targets&IC50: DGAT-2: 14 nM

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: PF-06424439 methanesulfonate can be used in drug discovery research to explore the potent and selective inhibition of DGAT2 in lipid metabolism.