Anacetrapib

Cat. No.: 0225LY-1236

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

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INQUIRY Datasheet MSDS

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Product Overview

Description: Anacetrapib is a reversible and specific inhibitor of CETP (IC50: 7.9 nM) that elevates serum HDL-cholesterol while lowering LDL-cholesterol levels.

Synonym: MK-0859; 875446-37-0; Anacetrapib; MK0859; Anacetrapib (MK-0859); (4s,5r)-5-[3,5-bis(trifluoromethyl)phenyl]-3-({2-[4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]-5-(trifluoromethyl)phenyl}methyl)-4-methyl-1,3-oxazolidin-2-one; (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl]-4-methyl-1,3-oxazolidin-2-one; 15a-Hydroxy Testosterone; (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one; MK 0859; (4S,5R)-5-(3,5-Bis(trifluoromethyl)phenyl)-3-((4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)methyl)-4-methyloxazolidin-2-one; (4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-((4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)methyl)-4-methyloxazolidin-2-one.

CAS No.: 875446-37-0

Compound CID: 11556427

Formula: C₃₀H₂₅F₁₀NO₃

Formula Weight: 637.51

Specification

Targets&IC50: CETP (recombinant human): 7.9 nM; CETP (mutant; C13S): 11.8 nM

Relative Density: 1.345 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Anacetrapib can be used in cardiovascular research to study the inhibition of cholesteryl ester transfer protein (CETP) and its effect on HDL levels.