Mevastatin

Cat. No.: OB0225WX-2589

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Mevastatin is a competitive antagonist of HMG-CoA reductase that binds to the enzyme with an affinity 10,000 times greater than that of the endogenous HMG-CoA substrate.

Synonym: ML-236B; Compactin; 73573-88-3; Mevastatina; Mevastatinum; Mevastatine; Antibiotic ML 236B; Compactin;ML236B; ML 236 B; MFCD05662341; [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate; Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-; (1S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-7-methyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthyl (S)-2-methylbutyrate; (1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate; 7-(1,2,6,7,8,8a-Hexahydro-2-methyl-8-(2-methylbutyryloxy)naphthyl)-3-hydroxyheptan-5-olide; (1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate

CAS No.: 73573-88-3

Compound CID: 64715

Formula: C₂₃H₃₄O₅

Formula Weight: 390.51

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Mevastatin is utilized in lipid metabolism and cell biology research as the first identified HMG-CoA reductase inhibitor to study the blockage of the mevalonate pathway and its effects on protein isoprenylation.