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Xanthatin
Cat. No.:
0225LY-1314
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Xanthatin possesses cytotoxic and antimicrobial activities against MRSA; it shows therapeutic potential for NSCLC and melanoma by inhibiting angiogenesis and modulating the Wnt/beta-catenin pathway to stop cell proliferation.
Synonym:
26791-73-1; (-)-Xanthatin; (3aR,7S,8aS)-7-methyl-3-methylidene-6-[(E)-3-oxobut-1-enyl]-4,7,8,8a-tetrahydro-3aH-cyclohepta[b]furan-2-one; (3aR,7S,8aS)-7-Methyl-3-methylene-6-((E)-3-oxobut-1-en-1-yl)-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one; (3aR,7S,8aS)-7-methyl-3-methylidene-6-[(1E)-3-oxobut-1-en-1-yl]-2H,3H,3aH,4H,7H,8H,8aH-cyclohepta[b]furan-2-one
CAS No.:
26791-73-1
Compound CID:
5281511
Formula:
C15H18O3
Formula Weight:
246.3
Specification
Targets&IC50:
T. b. brucei: 2.63 µg/mL (IC50); VEGFR2 kinase: 3.8 μM (IC50)
Relative Density:
1.1 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Xanthatin can be used in oncology research to explore the inhibition of tumor angiogenesis and the suppression of pro-inflammatory transcription factors.
Library Information
Target:
Lipoxygenase; VEGFR; Wnt/β-Catenin
Receptor:
Lipoxygenase; VEGFR; Wnt/β-Catenin
Pathways:
Metabolism; Cytoskeletal signaling; Angiogenesis; Apoptosis; Tyrosine kinase/adaptors; Stem cell regulation; Microbiology/Virology
Plate Number:
AOCL-17
Plate Location:
g11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
65 mg/mL; 263.91 mM
Solubility:
Soluble in chloroform, dichloromethane, ethyl acetate, acetone, etc.





