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TBB
Cat. No.:
0225LY-1285
Purity:
≥99%
Identity:
Confirmed by LC-MS.
Size:
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Product Overview
Description:
TBB is a highly selective inhibitor of Casein kinase-2 (CK2) that competes for ATP and GTP.
Synonym:
Casein Kinase II Inhibitor I; 4,5,6,7-tetrabromobenzotriazole; 17374-26-4; 4,5,6,7-Tetrabromo-1H-benzotriazole; TBBt; 4,5,6,7-tetrabromo-2H-benzotriazole; 4,5,6,7-Tetrabromo-1H-benzo[d][1,2,3]triazole; 4,5,6,7-Tetrabromo-2-azabenzimidazole; Casein Kinase II Inhibitor I; 1H-Benzotriazole, 4,5,6,7-tetrabromo-
CAS No.:
17374-26-4
Compound CID:
1694
Formula:
C6HBr4N3
Formula Weight:
434.71
Specification
Targets&IC50:
CK1: 47 μM(Ki); CK2: 0.4 μM(Ki)
Relative Density:
2.840 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
TBB can be used in signaling studies to explore the selective inhibition of Protein Kinase CK2.
Library Information
Target:
Casein kinase; GSK-3; CDK
Receptor:
CDK2; CK2; GSK-3β
Pathways:
Metabolism; Stem cell regulation; PI3K/Akt/mTOR signaling; Cell cycle/Checkpoint
Plate Number:
AOCL-17
Plate Location:
e2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 230.04 mM
Ethanol Max Solubility:
100 mM
