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Retinoic acid
Cat. No.:
0225LY-0533
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by HPLC.
Size:
Add to basket
Product Overview
Description:
Retinoic acid is a vitamin A metabolite and natural RAR agonist that inhibits RARα/β/γ (IC50 = 14 nM) to suppress tumorigenesis, limit proliferation, and promote differentiation.
Synonym:
Vitamin A acid; ATRA; All-trans-Retinoic acid; Tretinoin; 302-79-4; beta-Retinoic acid; all-(E)-Retinoic acid; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
CAS No.:
302-79-4
Compound CID:
444795
Formula:
C20H28O2
Formula Weight:
300.44
Specification
Targets&IC50:
RARα: 14 nM; RARβ: 14 nM; RARγ: 14 nM
Relative Density:
1.0597 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Retinoic acid can be used in cell differentiation studies or play a crucial role in investigating gene expression regulation through RAR and RXR receptors.
Library Information
Target:
Retinoid receptor; PPAR
Receptor:
PPAR; RAR/RXR
Pathways:
Metabolism; Autophagy; DNA damage/DNA repair
Plate Number:
AOCL-7
Plate Location:
h7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
95 mg/mL; 316.2 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
6 mg/mL; 19.97 mM
