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PK11007
Cat. No.:
0225LY-0553
Appearance:
Solid
Purity:
≥97%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
PK11007 is a specialized pharmaceutical agent classified as an anti-p53 drug.
Synonym:
874146-69-7; 5-Chloro-2-((4-fluorobenzyl)sulfonyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide; 5-Chloro-2-[[(4-fluorophenyl)methyl]sulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide; 5-chloro-2-[(4-fluorobenzyl)sulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide; 5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
CAS No.:
874146-69-7
Compound CID:
16446482
Formula:
C15H11ClFN5O3S2
Formula Weight:
427.86
Specification
Relative Density:
1.610 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
PK11007 can be used in tumor suppressor research to investigate the reactivation of p53 through the alkylation of its cysteine residues.
Library Information
Target:
p53; Mdm2
Receptor:
MDM2-p53 complex
Pathways:
Metabolism; Apoptosis; Immunology/Inflammation; NF-κB
Plate Number:
AOCL-8
Plate Location:
b7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 233.72 mM
