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Vitamin B12 test kit

LY518674

Cat. No.: 0225LY-0908
Appearance: Viscous
Purity: ≥98%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
LY518674
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Product Overview

Description: LY518674 is a selective and potent PPARα agonist (EC50: 42 nM for the human subtype) used to treat atherosclerosis by increasing HDL-C and lowering triglyceride levels.
Synonym: LY-674; 425671-29-0; LY518674; LY-674; Ly 518674; 2-Methyl-2-[4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propanoic acid; 2-Methyl-2-(4-{3-(1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)propyl}phenoxy)propanoic acid; Propanoic acid, 2-(4-(3-(2,5-dihydro-1-((4-methylphenyl)methyl)-5-oxo-1H-1,2,4-triazol-3-yl)propyl)phenoxy)-2-methyl-; 2-methyl-2-(4-(3-(1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)propyl)phenoxy)propanoic acid; 2-methyl-2-[4-[3-[1-[(4-methylphenyl)methyl]-5-oxo-2H-1,2,4-triazol-3-yl]propyl]phenoxy]propanoic acid; 2-methyl-2-[4-[3-[1-[(4-methylphenyl)methyl]-5-oxo-4H-1,2,4-triazol-3-yl]propyl]phenoxy]propanoic acid; 2-methyl-2-[4-[3-[2-[(4-methylphenyl)methyl]-3-oxo-1H-1,2,4-triazol-5-yl]propyl]phenoxy]propanoic acid
CAS No.: 425671-29-0
Compound CID: 135449333
Formula: C23H27N3O4
Formula Weight: 409.48

Specification

Targets&IC50: PPARα: 42 nM (EC50 human)
Relative Density: 1.21 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: LY518674 can be used in drug discovery to evaluate its efficacy as a highly selective agonist of the PPAR-alpha receptor.

Library Information

Target: PPAR
Receptor: PPARα
Pathways: Metabolism; DNA damage/DNA repair
Plate Number: AOCL-12
Plate Location: f8
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 250 mg/mL; 610.53 mM
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