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Diphylline
Cat. No.:
0225LY-0649
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Diphylline is a xanthine derivative used for emphysema, chronic bronchitis, and acute asthma; it likely functions as a competitive phosphodiesterase inhibitor—increasing intracellular cAMP to relax bronchial muscles—and may also serve as an adenosine receptor antagonist.
Synonym:
Diprophylline; 479-18-5; 7-(2,3-Dihydroxypropyl)theophylline; Lufyllin; Neothylline; Glyphylline; Protheophylline; Aristophyllin; Corphyllin; Neutrafillina; Neutraphyllin; Neutraphylline; Neutroxantina; Propyphyllin; Synthophylline; Hidroxiteofillina; Astrophyllin; Neostenovasan; Silbephyllin; Silbephylline; Asthmolysin; Coronarin; Glyfyllin; Hiphyllin; Hyphylline; Liactemin; Neotilina; Neutrafil; Purifilin; Solufilin; Solufyllin; Soluphyllin; Thefylan; Circain; Coronal; Droxine; Dyflex; Neophyl; Neufil; Tefilan; Teofen; Dilor; (1,2-Dihydroxy-3-propyl)thiophyllin; Dilor-400; 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine; 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione
CAS No.:
479-18-5
Compound CID:
3182
Formula:
C10H14N4O4
Formula Weight:
254.24
Specification
Relative Density:
1.3036 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Diphylline can be used in pharmacological studies to examine the bronchodilatory effects of xanthine derivatives.
Library Information
Target:
PDE; Adenosine receptor
Receptor:
Adenosine receptor; PDE
Pathways:
Metabolism; GPCR/G protein signaling; Neuronal signaling
Plate Number:
AOCL-9
Plate Location:
d5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
198 mg/mL; 778.79 mM
Water Max Solubility:
47 mg/mL; 184.86 mM
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
