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ST271
Cat. No.:
OB0225WX-1909
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
ST271 is a potent chemical agent that functions as an effective inhibitor of protein tyrosine kinases (PTK).
Synonym:
106392-48-7; ST 271; ST-271; 2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-; (E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide; 2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)acrylamide; (2E)-2-cyano-3-[4-hydroxy-3,5-bis(propan-2-yl)phenyl]prop-2-enamide
CAS No.:
106392-48-7
Compound CID:
6439072
Formula:
C16H20N2O2
Formula Weight:
272.34
Specification
Targets&IC50:
PTK(fMet-Leu-Phe): 6.7μM; PTK(PAF): 9 μM
Relative Density:
1.137 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
ST271 is utilized in oncology research as a targeted inhibitor of the RET signaling pathway to investigate the molecular mechanisms of growth inhibition in RET-dependent cancer models.
Library Information
Target:
Tyrosine kinases; Phospholipase
Receptor:
Phospholipase; PTK
Pathways:
Metabolism; Tyrosine kinase/adaptors
Plate Number:
AOCL-25
Plate Location:
d11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 183.59 mM
ALogP:
3.285
HBA_Count:
1
HBD_Count:
2
Rotatable Bond:
4
