Flunarizine dihydrochloride

Cat. No.: 0225LY-1449

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Flunarizine dihydrochloride is a selective calcium channel blocker with H1-blocking and calmodulin-binding properties used for vertigo, peripheral vascular disease, and migraine prevention.

Synonym: Flunarizine 2HCl; KW-3149;R14950; 30484-77-6; Flunarizine 2HCl; Flunarizine HCl; Flunarizine (dihydrochloride); 1-(Bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine dihydrochloride; Flunarizine (as hydrochloride); (E)-1-(Bis-(p-fluorophenyl)methyl)-4-cinnamylpiperazine dihydrochloride; 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride; 1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride; Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2)

CAS No.: 30484-77-6

Compound CID: 5282407

Formula: C₂₆H₂₈Cl₂F₂N₂

Formula Weight: 477.42

Specification

Targets&IC50: Ca2+ channel: 68 nM(Ki)

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Flunarizine dihydrochloride can be used in neuroscience research to study the blockade of calcium and sodium channels in migraine and epilepsy models.