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Cardamonin
Cat. No.:
0225LY-0633
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Cardamonin is a chalcone found in Alpiniae katsumadai that displays antioxidant, anti-inflammatory, antimicrobial, and anti-diabetic properties; it blocks several pathways, including mTOR, NF-kB, and Akt, to hinder breast cancer growth and is used in studies of renal fibrosis.
Synonym:
Alpinetin chalcone; 18956-16-6; Dihydroxymethoxychalcone; (E)-Cardamonin; (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one; 2',4'-dihydroxy-6'-methoxychalcone; 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one; 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (2E)-; (E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one; 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-; (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one; (E)-1-(2,4-dihydroxy-6-methoxy-phenyl)-3-phenyl-prop-2-en-1-one
CAS No.:
18956-16-6
Compound CID:
641785
Formula:
C16H14O4
Formula Weight:
270.28
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Cardamonin can be used in inflammatory research to investigate the inhibition of the NF-kappaB and JAK/STAT signaling pathways.
Library Information
Target:
COX; TRP/TRPV channel; Akt; STAT; mTOR; Wnt/beta-catenin; NF-κB
Receptor:
TRP channel; mTOR; NF-κB; Akt; STAT3; Wnt/β-Catenin; COX-2
Pathways:
Stem cell regulation; NF-κB; Neuronal signaling; Membrane transporter/Ion channel; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Oxidation-reduction; Cytoskeletal signaling; JAK/STAT signaling
Plate Number:
AOCL-9
Plate Location:
b9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
250 mg/mL; 924.97 mM
